Conjunctival malignant melanoma
Synonyms: Conjunctival melanoma
A rare eye tumor characterized by a flat to nodular conjunctival mass with variable pigmentation. It can arise in any part of the conjunctiva but most often presents on the bulbar surface near the limbus. Invasion of corneal tissue eyelid margin sclera or orbit may occur in advanced tumors. Metastatic spread most commonly involves regional lymph nodes or the lung liver and brain. Essential diagnostic criteria are stromal invasion and severe cytological and architectural atypia exceeding those expected in a naevus. Desirable criteria are demonstration of melanocytic markers by immunohistochemistry pagetoid growth mitotic activity invasion into cornea or skin ulceration and tumor necrosis.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Conjunctival malignant melanoma?
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