Laryngeal neuroendocrine tumor

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A rare head and neck tumor characterized by an epithelial neoplasm with evidence of neuroendocrine differentiation typically located in the supraglottic larynx. The tumor can be well moderately or poorly differentiated the latter group being subdivided into small cell or large cell neuroendocrine carcinomas. There is a strong association with tobacco use. Patients present with hoarseness dysphagia sore throat airway obstruction hemoptysis and rarely a paraneoplastic syndrome due to aberrant hormone production. Poorly differentiated tumors are highly aggressive with high rates of regional and distant metastasis.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version May 2024

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