Late-onset isolated ACTH deficiency

Get in touch with RARE Concierge.

Contact RARE Concierge

Late-onset isolated ACTH deficiency is a rare acquired pituitary hormone deficiency characterized by secondary adrenal insufficiency with normal secretion of anterior pituitary hormones except for ACTH. Patients present with weakness fatigue weight loss anorexia vomiting/nausea hypoglycemia and abnormally low serum ACTH and cortisol levels. Association with autoimmune disease such as Hashimoto’s thyroiditis has been described.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version July 2024

Newly diagnosed with
Late-onset isolated ACTH deficiency?

Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.

Get Concierge Help

Advocacy Organizations

Don't see your organization here. Let us know here.

Clinical Trials

For a list of clinical trials in this disease area, please click here.