Late-onset isolated ACTH deficiency

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Late-onset isolated ACTH deficiency is a rare acquired pituitary hormone deficiency characterized by secondary adrenal insufficiency with normal secretion of anterior pituitary hormones except for ACTH. Patients present with weakness fatigue weight loss anorexia vomiting/nausea hypoglycemia and abnormally low serum ACTH and cortisol levels. Association with autoimmune disease such as Hashimoto’s thyroiditis has been described.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version July 2024

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Late-onset isolated ACTH deficiency?

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