Leukoencephalopathy with calcifications and cysts
Synonyms: LCC | Labrune syndrome
A rare genetic cerebral small vessel disease characterized by leukoencephalopathy and cerebral calcification and cysts due to diffuse cerebral microangiopathy resulting in microcystic and macrocystic parenchymal degeneration. The condition can present at any age from early childhood to late adulthood and manifests as a progressive cerebral degeneration. Symptoms are variable but restricted to the central nervous systems and include among others slowing of cognitive performance seizures and movement disorder with a combination of pyramidal extrapyramidal and cerebellar features.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version December 2023
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Leukoencephalopathy with calcifications and cysts?
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