Metaplastic carcinoma of the breast

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Metaplastic carcinoma of the breast is a rare aggressive subtype of invasive breast carcinoma characterized by rapid growth relatively large tumor size and a tendency to metastasize to distant organs particularly the lungs with relatively less frequent involvement of the axillary lymph nodes. Histologically the tumor shows high-grade cellularity and heterologous differentiation including chondroid osseous pleomorphic/sarcomatoid spindled and squamous elements. Patients usually present with a fast-growing large well-circumscribed mobile lump in the breast which can become painful and involve the chest wall and the skin leading to ulceration.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version June 2024

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