Nelson syndrome

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A rare acquired endocrine disease characterized by the triad of diffuse skin and mucosa hyperpigmentation markedly elevated serum adrenocorticotropin (ACTH) levels and an enlarging corticotroph adenoma which manifest following total bilateral adrenalectomy performed for the treatment of Cushing’s disease. Additionally patients may present with headaches visual field defects cranial nerve palsy pituitary apoplexy diabetes insipidus panhypopituitarism and occasionally paraovarian or paratesticular tumors.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version May 2024

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Nelson syndrome?

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Advocacy Organizations

My Faulty Gene

My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

My Little Sunshine Foundation

My Little Sunshine is a non-profit foundation dedicated to educating people about the importance of fertility preservation and making fertility resources accessible to all.


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Clinical Trials

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