A rare acquired endocrine disease characterized by the triad of diffuse skin and mucosa hyperpigmentation markedly elevated serum adrenocorticotropin (ACTH) levels and an enlarging corticotroph adenoma which manifest following total bilateral adrenalectomy performed for the treatment of Cushing’s disease. Additionally patients may present with headaches visual field defects cranial nerve palsy pituitary apoplexy diabetes insipidus panhypopituitarism and occasionally paraovarian or paratesticular tumors.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
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My Faulty Gene
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