Post-transplant lymphoproliferative disease

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Synonyms: PTLD

A group of rare immunodeficiency-associated lymphoproliferative disorders characterized by lymphoid or plasmacytic proliferations developing in the context of immunosuppression in a recipient of a solid organ or stem cell allograft. The group includes non-destructive post-transplant lymphoproliferative disorders (PTLDs) polymorphic PTLD monomorphic PTLDs and classic Hodgkin lymphoma PTLD. Patients may have more than one type of PTLD in a single or in different locations. The most commonly involved sites are lymph nodes gastrointestinal tract lungs and liver although the disease may occur almost anywhere in the body. In solid organ transplant recipients PTLD may also involve the allograft.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version July 2024

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Clinical Trials

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