Primary progressive apraxia of speech

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Synonyms: PPAOS

Primary progressive apraxia of speech is a rare neurodegenerative disease characterized by impaired planning or programming of the movements for speech leading to phonetically and prosodically abnormal speech in absence at onset of any other neurological features (such as aphasia memory loss pyramidal signs). Patients usually present articulatory distortions/groping slow rate distorted sound substitutions and/or trial and error articulatory movements which begin insiduously and worsen over time.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version July 2024

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Primary progressive apraxia of speech?

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Advocacy Organizations

Project CASK

VISION Project CASK believes in a world free of the life limitations and debilitating effects of CASK gene disorders. ​MISSION To accelerate breakthroughs in research to develop treatments and a cure for CASK gene disorders. ​VALUES Collaboration. Transparency. Urgency.

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Clinical Trials

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