Squamous cell carcinoma of the oropharynx
A rare head and neck tumor characterized by a malignant epithelial neoplasm with evidence of squamous differentiation which may arise in association with high-risk HPV in a subset of cases. HPV-positive tumors have a strong predilection for the base of tongue and the palatine tonsils and typically present at an advanced clinical stage with cervical lymphadenopathy. They are associated with significantly better prognosis than HPV-negative tumors which more commonly involve the soft palate manifest as sore throat and difficulty in swallowing or a neck mass and occur in older patients. Smoking and alcohol consumption are important risk factors.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Squamous cell carcinoma of the oropharynx?
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