Tenosynovial giant cell tumor
Synonyms: Diffuse-type GCT | Diffuse-type giant cell tumor | Pigmented villonodular synovitis | TGCT | TSGCT
A rare benign proliferative disorder of the synovial membrane primarily affecting young adults (with a peak age of onset in the second to fourth decade of life) characterized by proliferative locally invasive tumor-like lesions usually involving a single joint tendon sheath or bursa (most commonly the joints of the knee and hip and rarely others such as the ankle shoulder and temporomandibular joints). It presents with pain and limitation of motion along with swelling heat and tenderness over the involved joint eventually leading to arthritic degeneration and significant locomotor deficit if left untreated. PVNS can recur in patients even after treatment.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Tenosynovial giant cell tumor?
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Advocacy Organizations
Life Raft Group
The mission of the Life Raft Group is to enhance survival and quality of life for people living with GIST through patient-powered research, education and empowerment, and global advocacy efforts. The LRG vision is to champion patient-powered science and drastically increase long-term survivorship for all cancer patients.
Clinical Trials
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