Synonyms: Pituitary thyrotrophic adenoma | TSH-oma | Thyroid stimulating hormone-secreting pituitary adenoma | Thyrotroph adenoma
A rare functioning pituitary adenoma characterized by the presence of a pituitary mass associated with high levels of circulating free thyroid hormones in conjunction with normal to high levels of TSH and unresponsiveness of TSH levels to TRH stimulation and T3 suppression tests typically manifesting with signs and symptoms of mild to moderate hyperthyroidism (e.g. goiter (most frequently observed) palpitation excessive sweating arrhythmia weight loss tremor) and/or tumor mass effect (such as headache visual field defects hypopituitarism). Occasionally cosecretion of prolactin and/or growth hormone may cause galactorrhea and/or acromegaly.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
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TSH-secreting pituitary adenoma?
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