X-linked intellectual disability-short stature-overweight syndrome

X-linked intellectual disability-short stature-overweight syndrome

X-linked intellectual disability-short stature-overweight syndrome is a multiple congenital anomalies syndrome characterized by borderline to severe intellectual disability speech delay short stature elevated body mass index a pattern of truncal obesity (reported in older males) and variable neurologic features (e.g. hypotonia tremors gait disturbances behavioral problems and seizure disorders). Less common manifestations include microcephaly microorchidism and/or microphallus. Dysmorphic features have been reported in some patients but no consitent pattern has been noted.