Progressive supranuclear palsy-parkinsonism syndrome
Synonyms: PSP-p | PSP-parkinsonism
An atypical variant of progressive supranuclear palsy (PSP) a rare late-onset neurodegenerative disease characterized by prominent early parkinsonism (tremor limb bradykinesia axial and limb rigidity) rather than falls and cognitive change. Over the years patients ultimately develop clinical features characteristic of classical PSP. Neuropathological characteristics includes tau pathology and neuronal loss in specific brain areas especially in the subthalamic nucleus and substantia nigra. The tau pathology is less severe than in classical PSP.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
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Progressive supranuclear palsy-parkinsonism syndrome?
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