Progressive supranuclear palsy-parkinsonism syndrome

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Progressive supranuclear palsy-parkinsonism syndrome

Synonyms: PSP-p | PSP-parkinsonism

An atypical variant of progressive supranuclear palsy (PSP) a rare late-onset neurodegenerative disease characterized by prominent early parkinsonism (tremor limb bradykinesia axial and limb rigidity) rather than falls and cognitive change. Over the years patients ultimately develop clinical features characteristic of classical PSP. Neuropathological characteristics includes tau pathology and neuronal loss in specific brain areas especially in the subthalamic nucleus and substantia nigra. The tau pathology is less severe than in classical PSP.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: // Data version September 2023.

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Advocacy Organizations

The Assistance Fund

The Assistance Fund (TAF) is an independent charitable patient assistance organization that helps patients and families facing high medical out-of-pocket costs by providing financial assistance for their copayments, coinsurance, deductibles, and other health-related expenses. We currently manage more than 80 disease programs, each of which covers all FDA-approved treatment for the disease named in the program. Since 2009, TAF has helped nearly 180,000 people access critical treatment for life-threatening, chronic, and rare diseases.

Genetic Support Network of Victoria

The Genetic Support Network of Victoria is an organisation that supports people living with genetic, undiagnosed and rare conditions and those who support them including community and families, patient support organisations, health professionals and industry. Our vision is our community flourishing and living their best lives.

Clinical Trials

For a list of clinical trials in this disease area, please click here.